Archive for the 'Medication' Category

Daily Aspirin Use Appears to be Beneficial in Women

In a new study of almost 80,000 women, aspirin use at low to moderate doses was associated with a reduced risk of all-cause mortality, largely due to death from cardiovascular disease. It’s very important to note, however, that women should not start taking daily aspirin without asking their doctor’s advice first. Aspirin can cause ulcers and dangerous bleeding in certain people.

Source: Archives of Internal Medicine, March 2007

FDA Alert: Use of Both Aspirin and Ibuprofen at the Same Time

Ibuprofen (Advil) has been found to interfere with the anti-platelet effect of low dose aspirin (81 mg per day), potentially rendering aspirin less effective when used for cardioprotection and stroke prevention. Patients who use immediate release aspirin (not enteric coated) and take a single dose of ibuprofen 400 mg should dose the ibuprofen at least 30 minutes or longer after taking aspirin, or more than 8 hours before aspirin ingestion to avoid attenuation of aspirin’s effect.

Other nonselective OTC NSAIDs, such as Aleve, should be viewed as having the potential to interfere with the antiplatelet effect of low-dose aspirin as well.  

Source: FDA, September 2006

Daily Aspirin Therapy Tops the List of Affordable and Effective Preventive Measures

A recent report by the National Commission on Prevention Priorities, has identified the top 25 clinical services that are the most effective, yet relatively affordable.

Topping the list of of affordable and effective preventive measures was daily aspirin therapy. Men older than 40 and women older than 50, and those with any others at risk for heart disease should ask their doctors about taking one aspirin on a daily basis. There are important precautions, however, with respect to aspirin, so it’s important to consult with your doctor before starting aspirin therapy. May 2006