Compulsive Gambling Linked with Requip and Mirapex
Two prescription medications commonly prescribed for Parkinson’s, and also used to relieve the symptoms of restless legs syndrome, have again been linked to compulsive gambling and hypersexuality. A recent study from the Mayo Clinic found that of 66 patients who were taking either pramipexole (Mirapex) or ropinirole (Requip) for Parkinson’s, seven developed one of the destructive behaviors which resolved after the medications were discontinued or the doses were reduced.
Previous studies have identified a link between these drugs and compulsive behavior as well. In addition to gambling and hypersexuality, therapeutic levels of the medications have also been associated with compulsive eating, as well as excessive shopping or spending. Less destructive behaviors such as compulsive gardening, excessive fishing or hobby work have also been related to these drugs.
Mirapex and Requip are used alone or with other medications to treat the symptoms of Parkinson’s disease. They are also used in lower doses to help relieve the symptoms of restless legs syndrome. They are in a class of medications called dopamine agonists. A natural substance in the brain, Dopamine is needed to control movement.
Patients, as well as spouses or family members, need to be aware of this potential dangerous side effect of these drugs. ”The onset can be insidious and overlooked until life-altering problems develop”, according to the researchers in an article in MedPage Today. Contact your health care provider if new symptoms arise while on either of these drugs.
Source: Bostwick J, et al “Frequency of new-onset pathologic compulsive gambling or hypersexuality after drug treatment of idiopathic Parkinson disease” Mayo Clin Proc 2009; 84: 310-316.
Source: “Parkinson’s Drugs May Increase Compulsive Behavior”, MedPage Today, April 9, 2009
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